Bürli, Roland W. : rechercher sur Z-Library

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1

Influence of an Ethynyl or a Buta-1,3-diynyl Group on the Chemical Shifts of Hydroxy Groups of Glucopyranoses

Bruno Bernet, Roland Bürli, Jinwang Xu, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

2002

Langue:

english

Fichier:

PDF, 187 KB

english, 2002

2

Structure-guided design of substituted aza-benzimidazoles as potent hypoxia inducible factor-1α prolyl hydroxylase-2 inhibitors

Mike Frohn, Vellarkad Viswanadhan, Alexander J. Pickrell, Jennifer E. Golden, Kristine M. Muller, Roland W. Bürli, Gloria Biddlecome, Sean C. Yoder, Norma Rogers, Jennifer H. Dao, Randall Hungate, Jen

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 381 KB

english, 2008

3

An efficient synthesis of 1,6- and 1,7-dibromo-3-aminoisoquinolines: versatile templates for the preparation of functionalized isoquinolines

Mike Frohn, Roland W. Bürli, Bobby Riahi, Randall W. Hungate

Journal:

Tetrahedron Letters

Année:

2007

Langue:

english

Fichier:

PDF, 124 KB

english, 2007

4

Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme

Tejeda, Gonzalo S., Whiteley, Ellanor L., Deeb, Tarek Z., Bürli, Roland W., Moss, Stephen J., Sheridan, Eamonn, Brandon, Nicholas J., Baillie, George S.

Journal:

Proceedings of the National Academy of Sciences

Année:

2020

Langue:

english

Fichier:

PDF, 2.43 MB

english, 2020

5

Oligosaccharide Analogues of Polysaccharides, Part 18 , Synthesis of Cyclic Hybrids of 2,2′-Bipyridine and Acetylenosaccharides

Roland Bürli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

1999

Langue:

english

Fichier:

PDF, 207 KB

english, 1999

6

Oligosaccharide Analogues of Polysaccharides, Part 22 , Synthesis of Cyclodextrin Analogues Containing a Buta-1,3-diyne-1,4-diyl or a Butane-1,4-diyl Unit

Barbara Hoffmann, Diana Zanini, Isabelle Ripoche, Roland Bürli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

2001

Langue:

english

Fichier:

PDF, 366 KB

english, 2001

7

Cyclische Acetylenosaccharideneuartige Cyclodextrin-Analoga

Dipl.-Chem. Roland Burli, Prof. Dr. Andrea Vasella

Journal:

Angewandte Chemie

Année:

1997

Langue:

german

Fichier:

PDF, 277 KB

german, 1997

8

Cyclic “Acetylenosaccharides”—Novel Cyclodextrin Analogues

Prof. Roland Bürli, Dr. Andrea Vasella

Journal:

Angewandte Chemie International Edition

Année:

1997

Langue:

english

Fichier:

PDF, 279 KB

english, 1997

9

Enantiomerically Pure and Highly Substituted Alicyclic α,α-Difluoro Ketones: Potential Inhibitors for Malarial Aspartic Proteases, the Plasmepsins

Christoph Fäh, Roland Mathys, Leo A. Hardegger, Solange Meyer, Daniel Bur, François Diederich

Journal:

European Journal of Organic Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 844 KB

english, 2010

10

Oligosaccharide Analogues of Polysaccharides. Part 7. Synthesis of a monosaccharide-derived monomer for amylose and cyclodextrin analogues

Roland Bürli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

1996

Langue:

english

Fichier:

PDF, 742 KB

english, 1996

11

Oligosaccharide Analogues of Polysaccharides. Part 12. Synthesis of ‘acetyleno-saccharide’-derived cyclodextrin analogues

Roland Bürli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

1997

Langue:

english

Fichier:

PDF, 2.02 MB

english, 1997

12

Oligosaccharide Analogues of Polysaccharides. Part 14:. Carbocyclic cyclodextrin analogues. Synthesis of all trimeric and tetrameric isomers by homo- and heterocoupling of 1,4-cis-diethynylated 1,5-anhydroglucitols

Roland Bürli, Andrea Vasella

Journal:

Helvetica Chimica Acta

Année:

1997

Langue:

english

Fichier:

PDF, 1.56 MB

english, 1997

13

Copolymerization of cyclopentene and carbon monoxide with palladium catalysts

Esther Amevor, Roland Bürli, Giambattista Consiglio

Journal:

Journal of Organometallic Chemistry

Année:

1995

Langue:

english

Fichier:

PDF, 662 KB

english, 1995

14

Discovery of a potent and selective c-Kit inhibitor for the treatment of inflammatory diseases

Ning Chen, Roland W. Bürli, Susana Neira, Randall Hungate, Dawei Zhang, Violeta Yu, Yen Nguyen, Yanyan Tudor, Matthew Plant, Shaun Flynn, Kristin L. Meagher, Matthew R. Lee, Xuxia Zhang, Andrea Itano,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 204 KB

english, 2008

15

DNA binding ligands with in vivo efficacy in murine models of bacterial infection: optimization of internal aromatic amino acids

Roland W. Bürli, Jacob A. Kaizerman, Jian-Xin Duan, Peter Jones, Kirk W. Johnson, Mari Iwamoto, Kiet Truong, Wenhao Hu, Timothy Stanton, Alfred Chen, Sofia Touami, Matthew Gross, Vernon Jiang, Yigong

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 285 KB

english, 2004

16

Potent hFPRL1 (ALXR) agonists as potential anti-inflammatory agents

Roland W. Bürli, Han Xu, Xiaoming Zou, Kristine Muller, Jennifer Golden, Mike Frohn, Matthew Adlam, Matthew H. Plant, Min Wong, Michele McElvain, Kelly Regal, Vellarkad N. Viswanadhan, Philip Tagari,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2006

Langue:

english

Fichier:

PDF, 161 KB

english, 2006

17

New ‘chemical probes’ to examine the role of the hFPRL1 (or ALXR) receptor in inflammation

Mike Frohn, Han Xu, Xiaoming Zou, Catherine Chang, Michele McElvaine, Matthew H. Plant, Min Wong, Philip Tagari, Randall Hungate, Roland W. Bürli

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2007

Langue:

english

Fichier:

PDF, 185 KB

english, 2007

18

Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation

Christopher M. Tegley, Vellarkad N. Viswanadhan, Kaustav Biswas, Michael J. Frohn, Tanya A.N. Peterkin, Catherine Chang, Roland W. Bürli, Jennifer H. Dao, Henrike Veith, Norma Rogers, Sean C. Yoder, G

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 506 KB

english, 2008

19

Discovery of amido-benzisoxazoles as potent c-Kit inhibitors

Roxanne K. Kunz, Shannon Rumfelt, Ning Chen, Dawei Zhang, Andrew S. Tasker, Roland Bürli, Randall Hungate, Violeta Yu, Yen Nguyen, Douglas A. Whittington, Kristin L. Meagher, Matthew Plant, Yanyan Tud

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 278 KB

english, 2008

20

Modulating N- versus O-arylation in pyrazolone-aryl halide couplings

Jennifer E. Golden, Shanina D. Sanders, Kristine M. Muller, Roland W. Bürli

Journal:

Tetrahedron Letters

Année:

2008

Langue:

english

Fichier:

PDF, 128 KB

english, 2008

21

DNA Binding Ligands with Excellent Antibiotic Potency Against Drug-Resistant Gram-Positive Bacteria

Roland W. Bürli, Yigong Ge, Sarah White, Eldon E. Baird, Sofia M. Touami, Matthew Taylor, Jacob A. Kaizerman, Heinz E. Moser

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 121 KB

english, 2002

22

Sequence-specific DNA recognition by polyamides

Peter B Dervan, Roland W Bürli

Journal:

Current Opinion in Chemical Biology

Année:

1999

Langue:

english

Fichier:

PDF, 125 KB

english, 1999

23

DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 2: C-terminal benzimidazoles and derivatives

Roland W. Bürli, Peter Jones, Dustin McMinn, Quan Le, Jian-Xin Duan, Jacob A. Kaizerman, Stacey Difuntorum, Heinz E. Moser

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 196 KB

english, 2004

24

DNA binding ligands targeting drug-resistant Gram-positive bacteria. Part 1: Internal benzimidazole derivatives

Roland W. Bürli, Dustin McMinn, Jacob A. Kaizerman, Wenhao Hu, Yigong Ge, Quinn Pack, Vernon Jiang, Matthew Gross, Martin Garcia, Richard Tanaka, Heinz E. Moser

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2004

Langue:

english

Fichier:

PDF, 197 KB

english, 2004

25

Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors

Essa Hu, Roxanne K. Kunz, Shannon Rumfelt, Ning Chen, Roland Bürli, Chun Li, Kristin L. Andrews, Jiandong Zhang, Samer Chmait, Jeffrey Kogan, Michelle Lindstrom, Stephen A. Hitchcock, James Treanor

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 776 KB

english, 2012

26

A network against failing hearts—Introducing the German “Competence Network Heart Failure”

Felix Mehrhof, Markus Löffler, Götz Gelbrich, Cemil Özcelik, Maximilian Posch, Hans-Werner Hense, Ulrich Keil, Thomas Scheffold, Heribert Schunkert, Christiane Angermann, Georg Ertl, Roland Jahns, Bur

Journal:

International Journal of Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 235 KB

english, 2010

27

DNA Binding Ligands Targeting Drug-Resistant Bacteria: Structure, Activity, and Pharmacology

Kaizerman, Jacob A., Gross, Matthew I., Ge, Yigong, White, Sarah, Hu, Wenhao, Duan, Jian-Xin, Baird, Eldon E., Johnson, Kirk W., Tanaka, Richard D., Moser, Heinz E., Bürli, Roland W.

Journal:

Journal of Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 216 KB

english, 2003

28

Structure-guided design, synthesis and biological evaluation of novel DNA ligase inhibitors with in vitro and in vivo anti-staphylococcal activity

Surivet, Jean-Philippe, Lange, Roland, Hubschwerlen, Christian, Keck, Wolfgang, Specklin, Jean-Luc, Ritz, Daniel, Bur, Daniel, Locher, Hans, Seiler, Peter, Strasser, Daniel Stefan, Prade, Lars, Kohl,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.79 MB

english, 2012

29

Design, Synthesis, and Biological Evaluation of Potent and Selective Class IIa Histone Deacetylase (HDAC) Inhibitors as a Potential Therapy for Huntington’s Disease

Bürli, Roland W., Luckhurst, Christopher A., Aziz, Omar, Matthews, Kim L., Yates, Dawn, Lyons, Kathy. A., Beconi, Maria, McAllister, George, Breccia, Perla, Stott, Andrew J., Penrose, Stephen D., Wall

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 3.82 MB

english, 2013

30

Self-Assembled Hexasaccharides: Surface Characterization of Thiol-Terminated Sugars Adsorbed on a Gold Surface

Fritz, Michaela C., Hähner, Georg, Spencer, Nicholas D., Bürli, Roland, Vasella, Andrea

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 184 KB

english, 1996

31

DNA Binding Ligands with Improved in Vitro and in Vivo Potency against Drug-Resistant Staphylococcus aureus

Hu, Wenhao, Bürli, Roland W., Kaizerman, Jacob A., Johnson, Kirk W., Gross, Matthew I., Iwamoto, Mari, Jones, Peter, Lofland, Denene, Difuntorum, Stacey, Chen, Hsiu, Bozdogan, Bülent, Appelbaum, Peter

Journal:

Journal of Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 80 KB

english, 2004

32

Discovery of Aryl Aminoquinazoline Pyridones as Potent, Selective, and Orally Efficacious Inhibitors of Receptor Tyrosine Kinase c-Kit †

Hu, Essa, Tasker, Andrew, White, Ryan D., Kunz, Roxanne K., Human, Jason, Chen, Ning, Bürli, Roland, Hungate, Randall, Novak, Perry, Itano, Andrea, Zhang, Xuxia, Yu, Violeta, Nguyen, Yen, Tudor, Yanya

Journal:

Journal of Medicinal Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 332 KB

english, 2008

33

Development of small-molecule therapies for autoimmune diseases

Bürli, Roland W., Haughan, Alan F., Hodges, Alastair J.

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 253 KB

english, 2010

34

Inter- and Intramolecular Annulation Strategies to a Cyclopentanone Building Block Containing an All-Carbon Quaternary Stereogenic Center

Penrose, Stephen D., Stott, Andrew J., Breccia, Perla, Haughan, Alan F., Bürli, Roland W., Jarvis, Rebecca E., Dominguez, Celia

Journal:

Organic Letters

Année:

2015

Langue:

english

Fichier:

PDF, 525 KB

english, 2015

35

Selective β-Hydroxyethylation at the N-1 Position of a Pyrazolone: Synthesis of Benzyl 1-(β-Hydroxyethyl)-5-methyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazole-4-carboxylate

Siegmund, Aaron, Retz, Daniel, Xi, Ning, Dominguez, Celia, Bürli, Roland, Liu, Longbin

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 235 KB

english, 2008

36

Potent, selective and CNS-penetrant tetrasubstituted cyclopropane class IIa histone deacetylase (HDAC) inhibitors

Luckhurst, Christopher Andrew, Breccia, Perla, Stott, Andrew J, Aziz, Omar, Birch, Helen L, Burli, Roland, Hughes, Samantha J, Jarvis, Rebecca E, Lamers, Marieke, Leonard, Philip M, Matthews, Kim L, M

Journal:

ACS Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 681 KB

english, 2015

37

An efficient and scalable process to produce morpholine-d 8

Ye, Naidong, Smith, Dan A., Reid, J. Gregory, Watson, David R., Daga, Pankaj, Gottschling, Stephen E., Duggan, Mark, Bürli, Roland W.

Journal:

Synthetic Communications

Année:

2017

Langue:

english

Fichier:

PDF, 822 KB

english, 2017

38

N-ethylmaleimide increases KCC2 activity by modulating transporter phosphorylation

Conway, Leslie C., Cardarelli, Ross A., Moore, Yvonne E., Jones, Karen, McWilliams, Lisa J., Baker, David J., Burnham, Matthew P., Bürli, Roland W., Wang, Qi, Brandon, Nicholas J., Moss, Stephen J., D

Journal:

Journal of Biological Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2017

39

11. Orexin-1 Receptor Antagonists as Novel Smoking Cessation Agents

Kenny, Paul, Kamenecka, Theodore, Voren, George, Duncan, Alexander, Howe, Matthew, Hollander, Jonathan, Damez-Warno, Diane, Lu, Qun, Bali, Purva, Burli, Roland, Gurrell, Ian, Mather, Robert J., Brando

Journal:

Biological Psychiatry

Année:

2018

Langue:

english

Fichier:

PDF, 60 KB

english, 2018

40

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

Bürli, Roland W., Wei, Huijun, Ernst, Glen, Mariga, Abigail, Hardern, Ian M., Herlihy, Kara, Cross, Alan J., Wesolowski, Steven S., Chen, Hongming, McKay, Ronald D.G., Weinberger, Daniel R., Brandon,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 734 KB

english, 2018

41

Development and characterization of a CNS-penetrant benzhydryl hydroxamic acid class IIa histone deacetylase inhibitor

Luckhurst, Christopher A., Aziz, Omar, Beaumont, Vahri, Bürli, Roland W., Breccia, Perla, Maillard, Michel C., Haughan, Alan F., Lamers, Marieke, Leonard, Phil, Matthews, Kim L., Raphy, Gilles, Stott,

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 786 KB

english, 2018